Human beings are directly responsible for more than 110,000 chemical substances which have been generated since the Industrial Revolution. Every year, we “invent” more than 2,000 new substances, most of them contaminants, which are emitted into the environment and which are consequently present in food, air, soil and water. Nonetheless, human beings are also victims of these emissions, and involuntarily (what is known in this scientific field as “inadvertent exposure”), every day humans ingest many of these substances which cannot be assimilated by our body, and are accumulated in the fatty parts of our tissues.

A total of 668 samples from pregnant women were used in this study, which was approved by the Ethical Commission of the San Cecilio University Hospital. Mothers were informed of the study's goals before giving their express consent.

Thanks to the gynaecologists, the nurses and the midwives who participated in the study, biological samples were extracted from the blood, the umbilical cord and the placenta during childbirth. The following day, an epidemiological survey was carried out by trained survey statisticians. The survey contained questions on the general data of the parents, their places of residence, profession, medical history, anthropometric information, age, tobacco habits, lifestyle and diet during pregnancy, among other factors.

The study made at the UGR has facilitated research into the association of the characteristics of parents, newborn babies and childbirth with exposure to pesticides found in the mothers' placenta. Among the aspects associated with a higher presence of pesticides we find an older age, higher body mass index, less weight gained during pregnancy, lower educational level, higher workplace exposure, first-time motherhood and lower weight in babies.

According to María José López, “we do not really know the consequences of exposure to disruptive pesticides in children, but we can predict that they may have serious effects, since this placenta exposure occurs at key moments of the embryo's development”. The research group to which María José López belongs, directed by Prof. Nicolás Olea Serrano, has conducted several studies which associate exposure to pesticides with neonatal malformations if the genito-urinary system, such as cryptorchidism (undropped testicles) and hypospadias (total fusion of the urethral folds).

The UGR researcher underlines the fact that, in spite of “inadvertent exposure”, “it is possible to control pesticide ingestion by means of a proper diet, which should be healthy and balanced, through consumption of food whose chemical content is low. Moreover, daily exercise and the avoidance of tobacco (which could also be a source of inadvertent exposure) are very important habits which help to control the presence of pesticides in our organisms.

The UGR researcher's work is framed within the objectives established in the research project ”Increasing incidence of human male reproductive health disorders in relation to environmental effects on growth-and sex steroid-induced alterations in programmed development” (Environmental Reproductive Health), directed and carried out by a multidisciplinary group of clinicians, basic researchers and epidemiologists at several institutions from countries such as Denmark, Finland or England and financed by the European Union (QLK4-1999-01422).

The University of Granada (UGR) was founded in 1531, under the initiative of Emperor Charles V. In this way, Granada asserted its vocation as a university city, open to different cultures, peoples and beliefs, continuing the tradition of the Arab University of Yusuf I (Madrassa, 14th century). With 475 years of tradition, the University of Granada has been an exceptional witness to history, as its influence in the city's social and cultural environment grew until it was to become, over a period of almost five centuries, an intellectual and cultural nucleus in Southern Spain in its own right. The University of Granada has also made a strong commitment to its future by fostering the development of quality research, whose guiding criteria are to stress traditional lines of research, to support investigation which - although less developed - may prove useful to a changing society and to forge bonds with firms and institutions. As a result of its growth in scientific production, the UGR is among the top Spanish universities. More than 400 research groups are working in all different areas of knowledge, in collaboration with both national and international research groups. The University of Granada offers to 81,600 students - 10 per cent of which are foreign students - 75 degree courses distributed in 28 centres. The UGR is the leading European destination for Erasmus/Socrates students, the most important Spanish university in graduation prizes, the third in the number of doctoral courses with the Distinction of Quality granted by the Ministry of Education and Science and the sixth in scientific production.

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